---
_id: '2031'
abstract:
- lang: eng
text: " Atomic force microscopy (AFM) is one of the microscopic
techniques with the highest lateral resolution. It can usually be applied in air
or even in liquids, enabling the investigation of a broader range of samples than
scanning electron microscopy (SEM), which is mostly performed in vacuum. Since
it works by following the sample surface based on the force between the scanning
tip and the sample, interactions have to be taken into account, making the AFM
of irregular samples complicated, but on the other hand it allows measurements
of more physical parameters than pure topography. This is especially important
for biopolymers and hydrogels used in tissue engineering and other biotechnological
applications, where elastic properties, surface charges and other parameters influence
mammalian cell adhesion and growth as well as many other effects. This review
gives an overview of AFM modes relevant for the investigations of biopolymers
and hydrogels and shows several examples of recent applications, focusing on the
polysaccharides chitosan, alginate, carrageenan and different hydrogels, but depicting
also a broader spectrum of materials on which different AFM measurements are reported
in the literature.\r\n "
alternative_id:
- '1734'
- '2865'
article_number: '1267'
article_type: review
author:
- first_name: Jnanada Shrikant
full_name: Joshi, Jnanada Shrikant
id: '231115'
last_name: Joshi
orcid: 0000-0001-6063-5989
- first_name: Sarah Vanessa
full_name: Homburg, Sarah Vanessa
id: '216742'
last_name: Homburg
- first_name: Andrea
full_name: Ehrmann, Andrea
id: '223776'
last_name: Ehrmann
orcid: 0000-0003-0695-3905
citation:
alphadin: 'Joshi, Jnanada Shrikant
; Homburg, Sarah Vanessa ; Ehrmann, Andrea: Atomic Force Microscopy
(AFM) on Biopolymers and Hydrogels for Biotechnological Applications—Possibilities
and Limits. In: Polymers Bd. 14, MDPI AG (2022), Nr. 6'
ama: Joshi JS, Homburg SV, Ehrmann A. Atomic Force Microscopy (AFM) on Biopolymers
and Hydrogels for Biotechnological Applications—Possibilities and Limits. Polymers.
2022;14(6). doi:10.3390/polym14061267
apa: Joshi, J. S., Homburg, S. V., & Ehrmann, A. (2022). Atomic Force Microscopy
(AFM) on Biopolymers and Hydrogels for Biotechnological Applications—Possibilities
and Limits. Polymers, 14(6). https://doi.org/10.3390/polym14061267
bibtex: '@article{Joshi_Homburg_Ehrmann_2022, title={Atomic Force Microscopy (AFM)
on Biopolymers and Hydrogels for Biotechnological Applications—Possibilities and
Limits}, volume={14}, DOI={10.3390/polym14061267},
number={61267}, journal={Polymers}, publisher={MDPI AG}, author={Joshi, Jnanada
Shrikant and Homburg, Sarah Vanessa and Ehrmann, Andrea}, year={2022} }'
chicago: Joshi, Jnanada Shrikant, Sarah Vanessa Homburg, and Andrea Ehrmann. “Atomic
Force Microscopy (AFM) on Biopolymers and Hydrogels for Biotechnological Applications—Possibilities
and Limits.” Polymers 14, no. 6 (2022). https://doi.org/10.3390/polym14061267.
ieee: J. S. Joshi, S. V. Homburg, and A. Ehrmann, “Atomic Force Microscopy (AFM)
on Biopolymers and Hydrogels for Biotechnological Applications—Possibilities and
Limits,” Polymers, vol. 14, no. 6, 2022.
mla: Joshi, Jnanada Shrikant, et al. “Atomic Force Microscopy (AFM) on Biopolymers
and Hydrogels for Biotechnological Applications—Possibilities and Limits.” Polymers,
vol. 14, no. 6, 1267, MDPI AG, 2022, doi:10.3390/polym14061267.
short: J.S. Joshi, S.V. Homburg, A. Ehrmann, Polymers 14 (2022).
date_created: 2022-07-14T17:48:39Z
date_updated: 2024-03-27T14:01:14Z
department:
- _id: '103'
doi: 10.3390/polym14061267
file:
- access_level: open_access
content_type: application/pdf
creator: aehrmann
date_created: 2022-07-14T17:48:19Z
date_updated: 2022-07-14T17:48:19Z
file_id: '2032'
file_name: _2022_Joshi_Polymers14_1267.pdf
file_size: 1305324
relation: main_file
success: 1
file_date_updated: 2022-07-14T17:48:19Z
has_accepted_license: '1'
intvolume: ' 14'
issue: '6'
keyword:
- nanoindentation
- elastic modulus
- peak force quantitative nanomechanical mapping
- KPFM
- interaction forces
- adhesion
- impedance
- adsorption
- ultracentrifugation
- drop deposition
language:
- iso: eng
main_file_link:
- open_access: '1'
url: https://www.mdpi.com/2073-4360/14/6/1267
oa: '1'
publication: Polymers
publication_identifier:
eissn:
- 2073-4360
publication_status: published
publisher: MDPI AG
quality_controlled: '1'
status: public
title: Atomic Force Microscopy (AFM) on Biopolymers and Hydrogels for Biotechnological
Applications—Possibilities and Limits
tmp:
image: /images/cc_by.png
legal_code_url: https://creativecommons.org/licenses/by/4.0/legalcode
name: Creative Commons Attribution 4.0 International Public License (CC-BY 4.0)
short: CC BY (4.0)
type: journal_article
urn: urn:nbn:de:hbz:bi10-20318
user_id: '216459'
volume: 14
year: '2022'
...